Anne Rombough was born in Chowan County, North Carolina in about 1754. In November 1772 Anne (also called Nancy, which a popular nickname for Anne) married John Horniblow. Her husband was the proprietor and owner of the King's Arms Tavern, one of Edenton's main gathering places which adjoined the county courthouse. There, Anne likely heard many spirited discussions about the revolutionary politics of the day. In 1774 she signed a nonimportation agreement that later became known as the Edenton Tea Party Resolves. She died sometime between 1774 and 1778, when her father wrote his will.